Bioinformatics Markets

by "The Librarian" on March 20, 2010

The life science informatics marketplace–known as bioinformatics–is set to expand as high-tech companies infiltrate this arena and biopharmaceutical companies incorporate key informatic solutions into their business strategies. This Publications believes that many of the segments of bioinformatics described in this report offer an unusual opportunity for accelerated expansion within the coming years. This study is arranged to provide an overview of bioinformatics market segments and offer evidence that these segments are poised for significant future growth. Each segment is accompanied by analysis and forecasts by product type and application. This analysis surveys the bioinformatics market and the latest information regarding emerging new products and industry trends. The study will quantify and qualify the bioinformatics market segments as an area of research, product development and investment. Forecasts of the bioinformatics market and an analysis of products in the worldwide information-processing market will provide a basis for understanding the significance of past developments and future possibilities within this market category.

1. Overview 81.1 Statement of Report 81.2 About this Report 81.3 Scope of this Report 101.4 Methodology 101.5 Executive Summary 112. Introduction 132.1 Global Bioinformatics Products Industry 142.2 Computers and Biology 152.3 Bioinformatics and the Internet 172.4 Company Evaluation Overview 172.5 Market Outlook 182.6 Competitive Structure 202.7 Applications of Bioinformatics 202.7.1 Medicine 202.7.2 Microbial Genomics 222.7.3 Agriculture 222.8 R&D 222.8.1 Allocation of R&D 232.8.2 Traditional Drug Discovery Process 242.8.3 Drug Discovery and Bioinformatics 262.8.4 Collaborative Agreements 272.9 The Human Genome Project (HGP) 272.9.1 Goals of the Human Genome Project 272.9.2 Benefits of the Human Genome Project 292.10 Barriers to Entry 292.11 Proteomics and Databases 302.11.1 Protein Database Standards 312.11.2 Future Trends 323. The U.S. Bioinformatics Market 333.1 Overview 333.2 Market Restraints and Drivers 353.2.1 Market Restraints 353.2.2 Market Drivers 364. Genomics 374.1 The Biotechnology Industry 374.2 The Development of a Genomics Market 394.2.1 Market Drivers 404.2.2 Market Restraints 404.2.3 Market Size and Growth Projections 404.2.4 The U.S. Genomics Market 404.3 Biochips and DNA Microarrays 404.3.1 Key Challenges 424.3.2 Freeware 424.3.3 New Tools 434.4 Bioinformatics 464.5 Disease Targets 464.6 Functional Genomics 474.7 Gene Sequencing 504.8 Gene Sequence Variation Detection 504.9 Comparative Genomics 514.10 Genome Database Arrays 514.11 High-throughput Genomics 534.11.1 High-throughput Technology 544.11.2 Lab on a Chip 544.12 Pharmacogenomics 554.13 Probe Arrays 574.13.1 Gene Expression Monitoring Arrays 574.13.2 DNA Analysis Arrays 594.14 Proteomics 604.15 Sequencing 614.16 Single Nucleotide Polymorphisms (SNPs) 614.17 Structural Genomics 634.18 Photolithography 634.19 Instrumentation 645. The Bioinformatics Industry 655.1 Definition and Role of Bioinformatics 655.1.1 Bioinformatics Sector Overview 665.1.2 The Future Status of Bioinformatics 675.1.3 Barriers to Growth 675.2 Types of Data and Bioinformatics Applications 675.2.1 Validated Core Modeling Technology 685.2.2 Broad Applicability 695.2.3 Data Management Compliant with Industry Standards 695.2.4 Open Architecture 695.2.5 Ease of Use 695.2.6 Increased Access 695.3 Functions of Bioinformatics Software 705.3.1 Data Management 705.3.2 Data Transformation 705.3.3 Data Collaboration 705.3.4 Interface for Online Data Sources 705.4 Target Markets for Informatics Software 715.5 Steps Involved in Bringing a Drug to Market 715.6 Costs Incurred in Developing a New Drug 725.7 Industry Drivers and Challenges 725.8 Industry Risks 745.9 Products of Bioinformatics 755.10 Bioinformatics Processes 765.11 Informatics Tools and Functionalities 765.11.1 Sequence to Structure 765.11.2 Lead Identification and Optimization 775.11.3 Development and Formulation 775.11.4 Improving Materials and Processes 775.11.5 Other Materials-Based Industries 785.12 Role of Bioinformatics in the Biotechnology Value Chain 785.13 Bioinformatics Market Segment 785.13.1 Databases 785.13.2 Hardware 805.13.3 Software 805.13.4 Bioinformatics Services 815.14 Bioinformatics Market Size 825.14.1 Sales and R&D 825.14.2 IT Budget 835.14.3 Projected Bioinformatics Market Size 845.15 Global Market Perspective 856. Bioinformatics Business 886.1 Bioinformatics Business Models 886.1.1 Changing Business Models 896.1.2 Competition for Pure Play Informatics Companies 916.1.3 Non-Profit Organizations 916.1.4 In-House Bioinformatics Solutions 916.1.5 Large IT Companies 916.2 Bioinformatics Target Disciplines 926.2.1 Comparative Genomics 926.2.2 Pharmacogenomics 926.2.3 Functional Genomics 926.2.4 Proteomics 936.2.5 Structural Genomics 946.2.6 Image Informatics 946.2.7 Clinical Trial Informatics 956.2.8 Cheminformatics 956.3 Bioinformatics Architecture 966.4 Bioinformatics Applications 976.4.1 Data Search Tools 976.4.2 Data Visualization Tools 976.4.3 Data Mining and Clustering 986.4.4 Enterprise Solutions 996.4.5 Data Warehousing 996.5 Evaluation of Bioinformatics Solutions 996.5.1 Requirements of Study 996.5.2 Shortlisting the Options 996.5.3 Scoring Patterns 1006.5.4 Performance 1016.5.5 Data Storage 1016.5.6 Data Management in Drug Discovery 1026.5.7 Key Issues in Bioinformatics Data Storage 1026.6 Convergence of Industries 1036.7 Proteins as a Driver 1046.8 Current Bioinformatics Research 1046.9 New Bioinformatics Modeling Algorithms 1056.10 3D Modeling 1056.11 Patenting Bioinformatics Algorithms 1067. Recent Industry Activity 1097.1 Collaborations and Acquisitions 1097.2 Product Development and Launches 1118. Corporate Profiles 1148.1 Abbott Laboratories 1148.2 Abgenix 1148.3 Ablynx 1158.4 Accelrys 1158.5 Affimed Therapeutics 1178.6 Affitech 1188.7 Affymetrix 1188.8 Agencourt Bioscience Corporation 1198.9 Agensys 1208.10 Agilent Technologies 1208.11 Alexion Pharmaceuticals 1218.12 AlgoNomics 1218.13 ALLEZ Software 1228.14 Amgen 1238.15 Antisoma 1248.16 Applied Biosystems 1248.17 Arana Therapeutics 1268.18 Ariadne Genomics 1278.19 Array Genetics 1278.20 Astellas Pharma 1288.21 AstraZeneca 1288.22 Automated Handling Systems 1298.23 Avesthagen, Limited 1308.24 Bioalma 1308.25 BIOBASE Biological Databases 1318.26 BioCarta 1328.27 Biodatabases (AMITA Corporation) 1328.28 BioDiscovery 1338.29 Biogen Idec 1338.30 BioInformatics 1348.31 BioInformatics Services 1358.32 BioInformatics Solutions 1358.33 Biomax Informatics 1368.34 BioServe Technologies 1368.35 Biosiris 1378.36 BioSoftSolutions 1378.37 Biotique Systems 1378.38 BioInvent International 1388.39 Biosite Discovery 1388.40 BioWa 1398.41 BioWisdom 1398.42 Bio-Xtal 1408.43 Boehringer Ingelheim 1408.44 Cambridge Antibody Technology Group 1418.45 Capital Genomix 1418.46 Celera Group 1418.47 Cellectis 1438.48 Cellomics 1438.49 CeuticalSoft 1448.50 Chemical Computing Group 1458.51 Cimarron Software 1458.52 CLONDIAG Chip Technologies 1468.53 CodonCode Corporation 1468.54 CompuDrug International 1468.55 Compugen USA 1478.56 Corimbia 1488.57 Crucell 1488.58 CSIRO Bioinformatics 1498.59 CuraGen Corporation 1498.60 CyberGene 1518.61 Cytogen 1518.62 Data Unlimited International 1518.63 deCODE Genetics 1518.64 Decodon 1528.65 Deltagen 1528.66 Digilab 1538.67 DNA Software 1548.68 DNAPrint Genomics 1548.69 DNA Star 1558.70 DxS 1558.71 Dyax Corp. 1568.72 Eisai 1578.73 Elan Corporation 1578.74 Electric Genetics Corporation 1598.75 Elusys Therapeutics 1608.76 Entagen 1608.77 Entelos 1608.78 Enzon Pharmaceuticals 1618.79 Epigenomics 1628.80 ePitope Informatics 1638.81 EraGen Biosciences 1638.82 European Bioinformatics Institute (EBI) Industry Programme 1638.83 Evolutionary BioInformatics 1648.84 Genamics 1648.85 GeneData 1648.86 Gene Logic 1658.87 Genentech 1678.88 Geneva Bioinformatics (GeneBio) 1688.89 Genmab 1698.90 GenOdyssee 1708.91 Genolyze 1708.92 Genomatica 1718.93 GenomeQuest 1718.94 Genomic Solutions 1728.95 Genomining 1738.96 Genovac 1738.97 Genzyme 1738.98 Geospiza 1758.99 GlaxoSmithKline 1768.100 Glycominds 1768.101 Health Discovery Corporation 1768.102 Hitachi Corporate Technology Group 1788.103 IBM Life Sciences 1788.104 ImClone Systems 1798.105 ImmunoGen 1808.106 Immunomedics 1818.107 Improved Outcomes Software 1838.108 INCOGEN 1848.109 Incyte Corporation 1848.110 Informagen 1858.111 Ingenuity Systems 1858.112 InNexus Biotechnology 1868.113 Insilicos 1868.114 Intrexon Corporation 1868.115 Invitrogen Corporation 1878.116 IO Informatics 1888.117 Johnson & Johnson 1888.118 LabVantage Solutions 1908.119 Lexigen 1908.120 Lifespan Biosciences 1908.121 Lion Bioscience 1908.122 MathEcology 1918.123 Matrix Science 1918.124 Medarex 1918.125 Medicel 1938.126 MedImmune 1938.127 Merus 1938.128 METabolic Explorer 1948.129 Metahelix Life Sciences 1948.130 Metalife 1948.131 Micromet 1958.132 Millennium Pharmaceuticals 1958.133 Molecular Connections 1968.134 Molecular Networks 1968.135 Molecularware 1968.136 MorphoSys 1978.137 Nexus Genomics 1978.138 Nonlinear Dynamics 1978.139 Novartis 1988.140 Ocimum Biosolutions 1998.141 OmniViz 2008.142 Partek 2008.143 PDL BioPharma 2018.144 Perlegen Sciences 2038.145 Philogen 2038.146 Philotec 2048.147 Prokaria 2048.148 Quantiom Bioinformatics 2048.149 Relevant Software 2058.150 Roche 2058.151 Rosetta Inpharmatics 2068.152 Sanofi-Aventis 2078.153 SBI Science 2098.154 Seascape Learning 2098.155 Seattle Genetics 2108.156 Scil Proteins 2118.157 Simulations Plus 2118.158 Spotfire 2128.159 Strand Life Sciences 2138.160 Sun Microsystems 2148.161 Symphogen 2158.162 Syngene 2158.163 Tahoe Informatics 2158.164 Tanox 2158.165 3rd Millennium 2168.166 ThromboGenics 2168.167 Thomson Reuters 2178.168 TIB MOLBIOL 2178.169 Trion Pharma 2178.170 Tripos 2188.171 UBI Life Sciences 2188.172 Viventia Biotech 2198.173 VizX Labs 2198.174 Wyeth 2208.175 Xcellerex 2208.176 Xencor 2218.177 Xoma 2218.178 Xpogen 223INDEX OF FIGURESFigure 4.1: Representation of Biotechnology Market, Geographically, 2008 38Figure 5.1: Informatics Applications along the Drug-Discovery Value Chain 65Figure 5.2: Functions of Bioinformatics Software in Research 65Figure 5.3: EMBL Database Growth, 1995-2008 66Figure 5.4: The Steps Involved in Bringing a Drug to Market 71Figure 5.5: The Breakdown of Total Costs in New Drug Development, 2007 72Figure 5.6: The Role of Bioinformatics in the Biotechnology Value Chain 78Figure 5.7: Worldwide Pharmaceutical Sales and R&D Expenditures, 2000-2013 83Figure 5.8: Worldwide Growth in IT Budget, 2000-2013 84Figure 5.9: Worldwide Bioinformatics Market, 2000-2013 85Figure 6.1: Steps of a Proteomics Experiment 94Figure 6.2: Bioinformatics Architecture 96INDEX OF TABLES Table 2.1: Leading Biotechnology Companies 21Table 2.2: Total of Domestic U.S. R&D, 2006-2013 24Table 2.3: Global Biotechnology Market, 2007 24Table 2.4: SIB Informatics Databases 31Table 4.1: The U.S. Biotechnology Industry Size and Revenue, 2000-2007 37Table 4.2: Global Biotechnology Industry Major Segments 39Table 4.3: Genomics Sector Market Size, 2006-2013 40Table 4.4: Total Biochip Market, 2007-2013 41Table 4.5: Selected Competitors in the Biochip Market 41Table 4.6: Biochip Microarray Products 41Table 4.7: Bioinformatics Tools 46Table 4.8: Functional Genomics Companies Building Advanced Integrated Platforms and Substantial Databases 49Table 4.9: Companies Using New Genomic Tools 50Table 4.10: Non-DNA–Based Chip Suppliers 51Table 4.11: Robotics or “Lab-on-a-Chip” Market Sector 51Table 4.12: Key High-throughput and Systemic Approaches in Genomic Analysis 53Table 4.13: Pharmacogenomics Segment Players 56Table 4.14: The Worldwide Market for Pharmacogenomics, 2006-2013 56Table 4.15: Competitors in the SNP Genotyping Segment 63Table 4.16: Scanning and Detection Technology Suppliers 64Table 5.1: Data Sources and Bioinformatic Investigations 68Table 5.2: Drivers and Challenges of the Bioinformatics Industry 73Table 5.3: Bioinformatics Activities, Sub-Activities and Key Players 81Table 5.4: Bioinformatics Market Size, 2006-2013 86Table 5.5: Cheminformatics Market Size, 2006-2013 86Table 5.6: In-silico Informatics Market Size, 2006-2013 86Table 5.7: Bioinformatics Hardware and Systems Market Size, 2006-2013 87Table 6.1: Alliances between IT/Telecom and Biotechnology Firms 103Table 6.2: Types of Intellectual Property Protection for Bioinformatics Tools 108http://www.aarkstore.com/reports/Bioinformatics-Markets-1172.html

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